Which condition can cause trouble breathing?

Cystic fibrosis is the correct choice because it is a genetic disorder that primarily affects the lungs and digestive system. In individuals with cystic fibrosis, the body produces thick and sticky mucus that clogs the airways, leading to difficulty in breathing, recurrent lung infections, and reduced lung function over time. This can manifest as shortness of breath, wheezing, and other respiratory issues that interfere with normal breathing patterns.

The other conditions listed do not primarily affect breathing. Juvenile diabetes primarily relates to issues with insulin production and does not directly impact respiratory function. Colon cancer affects the large intestine and does not have a direct connection to breathing difficulties, although advanced stages may indirectly affect overall health. Down Syndrome is a genetic condition that may include various health challenges, but it does not inherently cause trouble breathing across all individuals; respiratory issues could arise but are not a defining characteristic of the condition itself.